Prednisone (Prednisolone) is used to treat many different conditions. It is used to treat endocrine (hormonal) disorders when the body does not produce enough of its own steroids. It is also used to treat many disorders such as arthritis, lupus, severe psoriasis, severe asthma, ulcerative colitis, and Crohns Disease. Generic Prednisone is effective in reducing asthma attacks & the need for other medications to manage your symptoms.