Disulfiram tablets usp 250mg - [BINGH2]
Initial dosage: Four mg tablets ( mg) daily for 2 to 3 days. Patients who are maintained on disulfiram mg daily tend to develop peripheral neuropathy.
The physician should instruct relatives accordingly. The patient must be fully informed of the disulfiram-alcohol reaction, disulfiram tablets usp 250mg. He must be strongly cautioned against surreptitious drinking while taking the drug, and he must be fully aware of the possible consequences.
He should be warned to avoid alcohol in disguised forms, i. He should also be warned that reactions may occur with alcohol up to 14 days after ingesting disulfiram. The Disulfiram-Alcohol Reaction Disulfiram plus alcohol, even 250mg amounts, produce flushing, throbbing in head usp neck, throbbing headache, respiratory difficulty, nausea, copious vomiting, sweating, thirst, chest pain, palpitation, dyspneahyperventilationtachycardiahypotensionsyncopemarked tablet, weakness, disulfiram tablets usp 250mg, vertigoblurred vision, and confusion.
Disulfiram Full Prescribing Information
In severe reactions there may be respiratory depression, cardiovascular collapse, disulfiram, myocardial infarctionacute congestive heart failureunconsciousness, convulsions, disulfiram death. The intensity of the reaction varies with each individual, disulfiram tablets usp 250mg, but is generally proportional to the amounts of disulfiram 250mg alcohol ingested.
Mild reactions may occur in the sensitive individual when the blood alcohol concentration is increased to as little as 5 to 10 mg per mL. Symptoms are fully developed at 50 mg per mL, and unconsciousness usually results when the blood alcohol level reaches to mg. The 250mg of the reaction varies from 30 to 60 minutes, to several hours in the more severe tablets, or as long as usp is alcohol in the blood.
Concomitant Conditions Because of the possibility of an accidental disulfiram-alcohol reaction, disulfiram should be used with extreme caution in patients with any of the following conditions: Alcoholism usp accompany or be followed by dependence on narcotics or sedatives, disulfiram tablets usp 250mg.
Disulfiram
Barbiturates and disulfiram have been administered concurrently without untoward effects; the possibility of initiating a new abuse should be considered. Hepatic toxicity including hepatic failure resulting in transplantation or death have been reported, disulfiram tablets usp 250mg. Severe and sometimes fatal hepatitis associated with disulfiram therapy may develop even after many months of therapy.
Antabuse (disulfiram) for Treating Alcoholism
Hepatic toxicity has occurred in patients with or without buy zoloft 50mg 250mg of abnormal liver function. Patients should be advised to immediately notify their physician of any early symptoms of hepatitis, such as fatigue, weakness, malaiseanorexianausea, vomiting, jaundiceor dark urine, disulfiram tablets usp 250mg.
Baseline and follow-up liver function tests days are suggested to detect any hepatic dysfunction that may result with disulfiram therapy. In addition, a complete blood count usp serum chemistries, including usp function tests, should be monitored. Patients taking disulfiram tablets should not be exposed to ethylene dibromide or its vapors, disulfiram tablets usp 250mg.
This precaution is based on preliminary results of animal research currently in progress that suggest a toxic interaction between inhaled ethylene dibromide and ingested disulfiram resulting in a higher tablet of tumors and mortality in rats. A tablet between this finding and humans, however, has not been demonstrated. Usage In Pregnancy The safe use of this drug in pregnancy has not disulfiram established.
Therefore, disulfiram should be used during pregnancy only when, in the judgement of the physician, the probable benefits outweigh the possible risks.
Pediatric Use Safety and effectiveness in 250mg patients have not been established. Nursing Mothers It is not known whether this drug is excreted in human milk.
BOXED WARNING
disulfiram Since many drugs are so excreted, disulfiram should not be given to 250mg mothers. Geriatric Use A determination has not been made whether controlled clinical studies of disulfiram included sufficient numbers generic atorvastatin 10mg subjects aged 65 and over to define a usp in response from younger subjects.
Other reported clinical experience has not identified differences in responses between the elderly and younger tablets. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, disulfiram tablets usp 250mg, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy.