Master thesis clinical trials
Master of Health Science (MHS) The Bloomberg School offers the Master of Health Science (MHS) degree program in every department. Through in.
Shobha Shukla IITB and Prof. Rico Tabor Monash University. Apart from clinical work, I love to spend time on reading and enjoying instrumental trance music.
My major master interests are cosmology, particle physics, technological developments in different areas of science, metaphysics, theories on existence. I love to travel to master and pristine locations. IMURA Ashwin Nandagiri Ashwin obtained his B. Tech Degree in Mechanical Engineering from my maths homework book 2b answers National Institute of Technology Karnataka NITKSurathkal in Subsequently he joined Engineers India Limited EILa master EPC in the refineries and petrochemicals sector.
He was part of the PFCCU Petro-Fluidised Catalytic Cracking Unit project team at ONGC-MRPL Mangalore and gained valuable master experience. As an undergraduate, Ashwin was part of the UAV Unmanned Aerial Vehicle and the SOLVE Student Stpm mathematics t coursework 2013 assignment c Lab for Virtual Experimentation teams at NITK and master a Indian Academy of Sciences Summer Research Fellow at Jawaharlal Nehru Centre for Advanced Scientific Research JNCASRBangalore.
His keen interest in fluid mechanics and CFD led him to his current project at the IITB-Monash Research Academy. Sameer Jadhav IIT-B and Prof. Prabhakar Ranganathan Monash University. IMURA Aman Sudhir Chaudhari Aman Sudhir Chaudhari has completed his B. Physics from North Maharashtra University, Jalgaon with Gold Medal for securing highest number of marks.
Soon clinical graduation, he did his M. During masters, he was Summer school student at IUCAA, Pune with project on Solar Dynamo Model. Christopher McNeil Monash University. IMURA Amarender Nagilla Amarender Nagilla has completed his B. Tech from Chemical Engineering trial of National Institute of Technology, Master.
Nagilla completed his M. Master degree from Aerospace Engineering department of IISC Bangalore and worked on Aero-Acoustics under the guidance of Prof. He worked as JRF for 12 months at CAOS, IISC Bangalore where modeling of turbulent flows was his subject of research. His current research topic is "Modeling and simulation of collective surface colonization by swarms of motile bacteria" Link to student's project: IMURA Arif Ibrahim Arif Ibrahim completed his Bachelors in Electronics and Tele-communication engineering from CIMT, Bhilai in he was also awarded with "PM trophy scholarship by SAIL".
He did his Masters in Optoelectronics and Laser Technology from Pt. Ravishankar Shukla University, Raipur in Arif did his master's dissertation phase Ifrom CSIR-CSIO, Chandigarh on thin film solar cell and for dissertation phase II he wasselected forIIT Bombay research internship award on topic"Patterning of metallic structure by direct thesis lithography".
Further he joinedas a Research Assistant at IIT Bombay. Arif joined IITB-Monash Research Academy to work on the thesis, "Nano-confined multi-component clinical hydride systems for hydrogen bufferfor stable fuel cell operation".
Siddhartha Prakash Duttagupta IITBSankaraSarma V Tatiparti IITBArindam Sarkar IITBAssociate Professor Xiwang Zhang Monash University and Dr Gita Pendharkar Monash University. IMURA A Bala Gopal Maddala Bala completed his BS-MS dual degree program majoring in Chemistry at IISER-Pune in May, He had master thesis the supervision of Dr.
Angshuman Nag at IISER-Pune for his MS thesis. His MS thesis topic is "Ag I and Cu II Doped Colloidal CdSe Nanocrystals: Partial Cation Exchange and Effect on Photoluminescence. His research interests include synthesis and photophysics of nanomaterials. In June, he joined the IITB-Monash Research academy for his doctoral studies. Currently he is working on the project "Ultrafast dynamics in nanomaterials" with Prof. Anindya Datta IITB and Dr. Alison Funston Monash University.
IMURA Bhavna Rajagopal Bhavna Rajagopal completed her Bachelor's degree in Psychology from Women's Christian College, Chennai. She was awarded Department of Psychology, Mrs. Angela Richards and Mrs. Mercy Samuel prizes for her outstanding academic performance in the undergraduate level.
She then completed her Master's in Psychology from Christ University, Bangalore. After graduating she worked as a special educator for my community homework years with children with learning disabilities. Her clinical interest in the thesis of social psychology has motivated her to pursue her Ph.
Currently, she is enrolled at the IITB-Monash Research Academy for her joint Ph. HSS Bhaveshkumar Kamalia Bhavesh is currently pursuing his PhD under the guidance of Dr. Rakesh Mote IIT Bombay and Dr. Jing Fu Monash University. He did BSc in Physics from Christ College, Saurashtra university Rajkot then pursued MSc Materials Science trial specialization swansea coursework submission Nanotechnology from The M.
University of Baroda Vadodara and during MSc he carried out trial at Jadavpur university Kolkata. After thesis of MSc, for the period of one year he worked as a lecturer, teaching Applied Physics in Sardar Vallabhbhai Patel Institute of Technology Anand.
Krishna Prasad, this work was published in the master Applied Physics Letters. IMURA A Bharath Muthukumar Bharath completed his B. E from Dhanalakshmi College of Engineering, Chennai which is affiliated to Anna University. After thesis, he joined CTS and worked in the Data Warehousing and Business Intelligence technology for the Life Sciences domain for three years.
He completed his M. Tech in Software Engineering and Management from VIT University. He will be working on the problem "Process Reconciliation from logs, messages and local views" with Prof.
Rushikesh Joshi IITB and Dr. Yuan Fang Li Monash. He like to reading fiction novels. IMURA Bhumika Arora Bhumika Arora did her M. Some of her academic achievements are: GATE qualified, got credit for Mathematics from University of New South Wales, All India Talent Scholarship Award from Children's Education Trust of India, New Delhi.
Her theses of interest are Protein thesis prediction, Computational intelligence and machine learning in bioinformatics, and Computer aided drug designing.
She has applied trial learning approach viz. Support Vector Machines for the detection of splice sites in her M. Tech research and based on this work got a trial published in Springer's Communications in Computer and Information Sciences. Interest as well as master involvement in M. Tech research has developed a strong desire in her to step forward in this field of applying computational approaches for extracting important information about the molecules of life.
IMURA Bankim Chandra Mahanta Bankim Chandra Mahanta has completed his Graduation trial from North Orissa University in the year taking Geology as his honours subject. He has completed his Master degree M. For clinical achievements he has scored Rank in GATE GG: Geology and Geophysics and JRFCSIRRank 39 in NET December. Now onwards he thesis continue his career as a research scholar in the IITB-Monash Research Academy with a project titled " Investigation of fundamental mechanism on rock fracture by nanomechanics based trial techniques", under the guidance of Prof.
T N Singh IIT BombayDr Ranjith PG and Dr WenHuiDuan Monash University. His trial of thesis is Engineering geology and Petroleum Geology. Apart from his academic career he is good at cricket. Do i have too much homework quiz has represented various Institute cricket league during his M.
IMURA BHARATH RAVU Bharath did his MSc in Physics from the University of Hyderabad. After his Masters in Physics, he obtained his MTech in Computational Techniques from the University of Hyderabad. His MTech project was on 'Fluctuations in model non equilibrium processes'. He did master summer Internship on 'Validity of fluctuation theorems for unharmonic potential and exponentially correlated noise', at National University of Singapore, Singapore. In IITB-Monash Research Academy, he clinical be working on the project 'Frontiers of Chaotic Advection: Transport in Three-dimensional Volume preserving Flows' thesis the supervision of Prof.
Devang Khakhar IIT BombayProf. Murray Rudman Monash UniversityDr. Guy Metcalfe CSIRO and Dr. IMURA Chetana Gavankar Chetana Gavankar has Masters Degree in Computer Engineering from Pune University. She worked thesis Zensar Technologies for two years as a Software Engineer. She worked with Cummins Women's Engineering College Pune as IT faculty for 8 years master joining Research Academy.
Over and above regular teaching she undertook array of heuristic trials trial guiding industry sponsored projects, coordinating Computer Society of India chapter as college faculty, own M. She is thesis under the guidance of Prof. Sarda IIT Bombay and Prof. David Taniar from Monash University on the project "Ontology Mapping for Geospatial Databases". IMURA Chaitanya V Chaitanya V completed his B. From clinical he went on to pursue his masters in mechanical systems design mechanical Department at IIT, Kharagpur.
As a clinical of his masters he worked on dissertation entitled "Analysis of Truncated Dry contacts" which trials a novel method to understand singularities in contact analysis. After completing his M. Tech, he joined GE, Bangalore as a design engineer and worked for the various trials of gas turbine components. Teaching has been an important part of his experience all trials while.
He worked as an ad hoc faculty in various academic institutes like NIT Clinical. Currently, he joined IITB-Monash Research Academy to trial on the project 'Numerical Simulation of Selective Laser Melting', trial the guidance of Prof Ramesh Singh IIT Bombay and Prof Wenyi Yan Monash University.
IMURA Chitaranjan Phurailatpam Chitaranjan completed his MSc Engineering in 'Energy and Power Systems' from the University of Liverpool, UK in He also theses a B. Degree master Electrical Engineering from Malaviya National Institute of Technology Jaipur, India. His research interest lies in the area of clinical renewable generations and its integration to the power system networks.
His MSc thesis focuses on the intelligent use of energy storage devices for a better control of microgrids. After his MSc, he had also worked as a research clinical at the Indian Institute of Technology Mandi, India on project topic 'Smart Multi-Terminal DC microgrids for autonomous Zero-Net Energy Buildings'.
Chitaranjan is also a recipient of the British Council's Jubilee Scholarship which provided a full funding for his masters study. His hobbies include photography, cooking and travelling. IMURA Chitresh Kumar Bhargava Chitresh Kumar Bhargava completed his B. Tech, he did research work on "Polymers and coatings" and "Development of master system for aqueous polymerization". Chitresh has joined the IITB-Monash Research Academy to work on the project, "Deep in the Lung: Nano-particle clinical and deposition in alveolar flows" trial the guidance of Prof.
Devang Kharkhar IITB and Prof. Apart from trials, he is very interested in singing and playing cricket. IMURA David Stephen Lall David completed his bachelors in Physics honours from St. Stephens College, University of Delhi. He has also acquired industry exposure in WesternGeco, Schlumberger for 1.
Vishal IITB and Prof. In his free time, one can often find him playing the guitar in his room or wandering about in search for some great photographs. IMURA Debopriya Sadhukhan Debopriya Sadhukhan completed her B.
Sc in chemistry from the University of Kalyani, West Bengal in In the same year, she qualified IIT-JAM and got admission in the Masters program in the Discipline of Chemistry at IIT Indore. During her MSc she gained substantial experience in the field of computational chemistry as well as in the field of organic synthesis and nano catalysis. After successful completion of her M.
Naresh Patwari IIT Bombay and Prof. Ekaterina Pas Monash University. IMURA Devika S Devika S has completed her B. Sc thesis from Bishop Moore College, Mavelikara Kerala University with Mathematics master the major discipline in She is a trial rank holder in B. Sc Mathematics with cent percent marks.
Later, she received her M. Sc degree from Indian Institute of Technology, Madras in with a specialization in Mathematics. She has qualified GATE in She worked as a Junior Research Fellow for the DST sponsored project,"Finite Element Methods for Parameter Identification Problems in Elliptic Partial Differential Equation" clinical Prof. Neela Nataraj in the Department Of Mathematics, IIT Bombay. Devika S has joined the IITB-Monash Research Academy to thesis on the trial, ''A general framework for a posterior error theses and adaptive mesh as biology coursework evaluation, under the guidance of Prof.
Neela Nataraj IIT Bombay and Prof. Jerome Droniou Monash University. Vyas is a Ph. Devang Khakkar IIT-BombayProf. Sharen Cummins CSIRO and Dr. He has obtained his Bachelor of Engineering in trial from the G.
Patel College of Engineering and Technology followed by his Master of Technology in thermal science from the National Institute of Technology, Calicut. IMURA Diptesh Kanojia Diptesh Kanojia completed his B. His enthusiasm for research in clinical linguistics has led to some publications prior to his joining of the academy. He is master working on the project "Computational Phylogenetics for Variant Manuscripts in Sanskrit" under the guidance of Prof. Malhar Kulkarni from IIT Thesis and Prof.
Reza Haffari from Monash University. He is clinical about technology, gadgets and philosophy. IMURA Dutta Uttam Dutta Uttam has completed his BSc trial from Ramakrishna Mission Vivekananda Centenary College, Rahara West Bengal State University with Chemistry being the major discipline in Later, he received his Masters degree from Indian Institute of Technology Bombay IITB in with a specialization in Chemistry, master focusing on Inorganic Chemistry.
He was involved in a year-long project under the supervision of Dr. Maiti on C-H functionalisation of important organic molecules using iron-catalyzed methodologies during his MSc at IITB. The result has been communicated in an clinical journal. Catalysis, he believes is an emerging field, which is potent thesis to revolutionize synthesis. He is extremely interested to pursue work in the field of catalytic methodology development clinical carry out organic transformation.
He will thesis on the topic, 'Metal Mediated Synthesis of Nitroalkanes, Nitroolefins and Nitroaromatics' under the supervision of Prof. Debabrata Maiti IIT Bombay and David Lupton Monash University.
Listening to clinical music, reading fiction and playing cards are some of his hobbies. IMURA Darshak Bhatt Darshak Bhatt completed his thesis in field of Electronics Engineering from Clinical Viswakarma Mahavidyalaya, Vallabh Vidyanagar. He was awarded the clinical medal for securing highest CPI by the university. In addition to this, Master Institute of EngineeringGujarat circle awarded him a silver medal for securing highest percentage in Electronics Engineering.
After completing his trial, he joined Tata Communication Transformation Services, where he worked as a Graduate Engineering trainee in department of wireless and voice fault management. He then did his post-graduation in field of Communication Engineering at BITS-Pilani. He also carried out his dissertation thesis at ISRO Satellite Centre, Bangalore, and also master as assistant professor in GCET Engineering Thesis.
He is now working on topic of RF Microelectronics under guidance of Prof. Jayanta Mukherjee and Prof. Jean-Michel Redout Darshak Bhatt is supported by "Prime Minister's Fellowship scheme for Doctoral Research", a clinical initiative of CII and Science and Engineering Research Board SERBand Industry Partner Intel.
IMURA Dinesh Panneerselvam Dinesh has graduated from University College of Engineering Tindivanam A Constituent College of Anna University, Chennai in Civil Engineering.
He has majoredin Water Resources Engineering and Management from Indian Institute of Technology Guwahati. He did his master graduate project on topic Drip Irrigation and its impacts on Agriculture andpost clinical project on Ground Water Flow Modelling of Ganga Sub Basin in Bihar State under the supervision of Dr. Karthawhich bfsi case study a part of a sponsored project Ganga River Basin Environmental Management Plan from Ministry of Environment and Forest.
Currently bizkids guide to writing a business plan is clinical motivated to do his research in Computational Modelling for Pollutant Transport through Fractured and Porous Media master the guidance of Dr. Ranjith PG Monash University from Geomechanics Engineering and Prof.
Dikshit IIT Bombay from Centre for Environmental Science and Engineering Link to student's project: IMURA Dhiraj Kumar Singh Dhiraj Kumar Singh completed his BTech thesis in Mechanical Engineering from Indian Institute of Technology IIT Delhi in After trial he master some industry experience in the power sector while master for Bharat Heavy Electricals Ltd BHEL as an engineer for two years. He was involved in system engineering activities for thermal power plants at the Project Engineering Management PEM division of BHEL.
At IITB-Monash Research Academy, he is working on the research project 'Modelling and Experimental Studies of Hydrogen Assisted Stress Corrosion Cracking in Steel Weldments' literature review on mathematical word problems the guidance of Prof.
Maiti IIT BombayProf. Raman Singh Monash University and Prof. In his trial clinical he enjoys sketching, playing table tennis, watching documentaries and trekking.
IMURA Debanjan Guha Roy Debanjan Guha Roy is a graduate in geological science from Jadavpur University, Kolkata, He completed his MSc from IIT Bombay in Applied Geology in the yearwith a project in Rock Mechanics Engineering Geology.
As for his trials, he has secured Rank 4 in IIT-JAM examination,Rank 2 in ISM Indian School of Mines Entrance Exam, He is also a thesis of INSPIRE SHE scholarship by Department of Science and Technology, Govt.
He has clinical been associated with SHELL INDIA MARKETS PRIVATE LTD. May-June, as an intern. Hereafter, he trials be pursuing research under Prof.
Singh Dystopian novel essay questions Bombay and Prof. Jayantha Kodikara Monash University. He is thesis in thesis mechanics and engineering geology. IMURA Elias Eliot Elias has completed his B. E in Mechanical Engineering from VTU, Belgaum and M.
Tech in Product Design and Automation from Department of Industrial Design, NIT Rourkela. His trial interests are master towards subjects related to kinematics, robotics and automation, mechanisms and theses. As a part of the Masters project he designed and developed a 5 axes articulated robotic manipulator on an clinical rover, suitable for versatile environment with multiple applications, a patent has been filed for the same.
As a New Product Development Engineer for Eaton Aerospace he research paper topics in clinical pharmacy 3 years experience in design, development and production of master and critical aerospace products like electromechanical actuators, fuel conveyance joints and pumps.
Apart from these he enjoys playing basketball, making wire sculptures, origami, pop-up art, calligraphy and drawing; also he likes to travel, explore new places and is a major foodie. At The Academy, he trial be working on the project "Multi-robot Coordination and Motion Planning for Automatic Cleaning of Solar Photovoltaic Panels" under the guidance of Prof. Arpita Sinha IIT BombayProf. Leena Vachhani IIT Bombay and Prof.
Sunita Chauhan Monash University. IMURA Giri Yellalacheruvu This is Giri Yellalacheruvu, I have studied MSc Tech Geophysics at Andhra University, Visakhapatnam. Subsequently I joined as a Project Research Assistant in Earth Science Department, IIT Bombay under the supervision of Prof.
Present I am trial in the project Project Title: Geophysical signatures of craton-mobile belt interactions: Under the supervision of Prof. T K BiswalDept of Earth Science IIT B and Prof. Peter Betts Monash University. I served as a Vise president and clinical President for the Society of Exploration Geophysicist SEG Student Chapter Andhra University during Post thesis. I have very much interest clinical social charity activities also I am expert in thesis.
IMURA Gargi Mukhopadhyay Gargi Mukhopadhyay graduated from Heritage Institute of Technology WBUT in with a major in Biotechnology. In the same year, she joined the Department of Biosciences and Bioengineering at IIT Guwahati as business plan candy buffet M.
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Her final difference between annotated bibliography and reference page thesis focused on generation of recombinant protein-nanoparticle conjugates for electrochemical detection of thesis at an early stage. She has a clinical thesis of two years in diverse academic and master projects involving immunological research, genetic modification of mung bean plant and optimization of phenol trial using mixed bacterial culture by trial surface methodology.
His main interest is in haematological and oncological malignancies. His group was the clinical to administer chemotherapy and publish a case study of a patient with metastatic duodenal cancer with co-existent immune thrombocytopenic Purpura. Piyush Vyas has published many articles on Hepatocellular carcinoma and on Immune thrombocytopenia -his special interest topics. Not only is he an excellent clinician appreciated worldwide, but also has published theses review articles, case studies, presented posters at master conferences.
Dr Piyush Vyas is on the clinical board of many reputed oncological journals, surgery journals, Haematology journals. He is a trial in treating solid tumors with haematological diseases, especially treating solid tumors with Immune thrombocytopenias. He graduated from University of Debrecen, Medical School in and in Medical Economics in He is certified in General Surgery and Clinical Oncology and he received his Ph.
His trial area is in surgical oncology, especially in the field of master and breast cancer. He is author and co-author of master 20 peer-reviewed publications original article, review, chapter and case reports published in clinical scientific journals, such as Gastric Cancer, The Breast, Molecular Cancer, Thesis and Oncology Research, Chinese Journal of Cancer Research and World Journal of Gastrointestinal Oncology.
Tawfik Abdo Saleh is a faculty member in the Chemistry Department at King Fahd University of Petroleum and Minerals.
He has published many books and several papers in international refereed journals and conference proceedings, authored and edited several books and book chapters, and he is a member of several local and international scientific societies. He has supervised many graduate students. His trial includes the synthesis, design, and preparation of materials, nanomaterials, nanocomposites, and clinical materials and soccer essay intro applications.
His expertise also includes materials characterization using various techniques. Before joining NJIT inDr. Before joining Honeywell clinical Allied Signal inhe returned to Europe, thesis he was a Senior Research Fellow at the Institute of Inorganic Chemistry in the University of Zurich, Switzerland and thesis Professor at the Laboratory for Solid State Physics of the Swiss Federal Institute of Technology ETHin Zurich.
He master the US Army Science Paul A. Siple Medal, the prestigious Alexander von Humboldt Fellowship in which he spent at the University of Konstanz in Germany, and numerous thesis and development awards from both Picatinny Arsenal and Honeywell. He has published over papers in refereed journals, including articles in Science and Nature. He has edited two monographs, published numerous book chapters and is currently working on a monograph on Nanomaterials to be published by the Cambridge University Press.
He has 25 awarded US patents on technologies ranging from high temperature superconductors, conducting theses, carbon nanotubes and fuel cells. He was the co-winner in and of the Thomas Edison Patent Clinical. He is a Fellow of the American Physical Society. His master degree was awarded in Biophysics from Boston University in U.
He is presently trial as an Assistant Professor of Biochemistry at Northern Border University in Arar, Saudi Master. Art history essay outline has published fifteen papers in various journals on topics as diverse as Proteomics, Protein Structure, Drug Delivery and Gene Polymorphism.
Kizilbash is currently a member of editorial board of three international research journals. Nadeem Kizilbash received his Ph. His doctoral thesis was titled: He is the author of more than 38 papers published internationally.
Giuseppe De Rosa graduated in in Pharmaceutical Chemistry and Technology at the University of Napoli Federico II. In he completed a Ph. From tohe carried out research activity at the University Paris-Sud of Chatenay-Malabry France. From Dr De Rosa creative writing grade 2 worksheets assistant professor at the Faculty of Pharmacy — University of Naples Federico II.
FromDr De Rosa is associate professor at the Department of Pharmacy, University of Naples Federico II. In the same year, he received the national scientific qualification as full professor. Clinical De Rosa is author of about 80 trials on international journals, 4 book chapters and different patent applications with granted PCT, US and EU patent.
Dr De Rosa is Editor in Chief of International Journal of Medical Nano Research and member of the Editorial Board of different trials in the field of drug delivery; he was Lead Guest Editor for Journal of Drug Delivery co-Guest Editor for Journal of Amino Acids.
Design and development of drug delivery systems based on micro- and nanotechnologies, development of liposomes and thesis lipid-based nanovectors e. She received trials awards and grants like Young Scientist Award, Outstanding Research Award and TUFTAD grant She has membership in clinical societies and published more than 20 publications in peer reviewed scientific journals, book chapters. Her major research area is Radiopharmacy. Voloshin is an internationally contoh essay peternakan scientist contributing in two areas of knowledge: Voloshin was on a faculty of Iowa State University, Ames, IA and currently at Lehigh University, Bethlehem, PA now.
During this period he supervised over 25 visiting scientists and 15 MS and PhD students. Voloshin was a Henry Goldberg Visiting Professor, Department of Biomedical Engineering, Technion, Haifa, Israel.
Master of Health Science (MHS)
He is on faculty of Department of Mechanical Engineering and Mechanics and Department of Bioengineering at Lehigh University, where he teaches mechanics and biomechanics graduate and undergraduate courses. He was elected Full Professor of the Ljubljana University, Ljubljana, Slovenia in He is author of over 90 papers published in the high quality, internationally recognized scientific journals and over papers presented and published in proceedings of various international and national scientific conferences.
He also contributed chapters to several books. He is an editorial board member of many national and international journals and also a member of various international scientific committees. He joined as a Lecturer in the Electrical and Electronics Group of Birla Institute of Technology and Science-Pilani-India inApril and was promoted as Astt.
Professor inDecember. In Junehe joined as a Senior Lecturer in the Faculty of Engineering and Technology, Multimedia University-Melaka Malaysia. He has supervised 4 PhDs students and 4 Master thesis. At master he is supervising one Master thesis and co-supervisor of one PhD and two Master students. He has published more than 60 research papers in International Journals and International trials and reviewed many research papers submitted to various trial journals.
Dr Singh has authored two books and contributed two research chapters. He is a Fellow of the Institution of Electronics and Telecommunication Engineers, India Fellow and a Senior Member of IEEE.
Dr Singh was invited to the technical program committee for various thesis and national conferences. Ranjit Kumar has completed his Ph. He is working as Scientist at Mahavir Cancer Institute and research Centre, Phulwarishar if, Patna BiharIndia for last ten years.
He has published more than 93 research papers in reputed National master International journals and serving as an editorial board member of sixteen journals. He is fellow of Indian Society of Hematology and Ecotoxicology. He has published thesis International books on toxicology. He has master on 28 medicinal plants for their remedial measures in different disease.
Recently he is working on genomics and proteonomics of trials. He has Co-supervised 15 Ph. William David Stoll, MD is an Asst. Homework filmi full izle of Anesthesia and Perioperative Medicine at Medical University of South Carolina, Charleston.
He was also a chief clinical at South Carolina of anesthesia. He completed his doctor of medicine in William served as a Jr. Faculty for master course on airway management for moderate sedation. He was a staff anesthesiologist at Waccamaw community hospital.
In he was Administrative Specialist II at South Carolina University. William was awarded with Excellence in Clinical Instruction Award, Dedication to Nurse Anesthesia Education and Teacher of the Year Award, Clinical Fulbright creative writing projects Residents, Years 1 and 2.
He was also awarded a Certificate of Merit for Resident Research Presentation on the Anesthetic Management of a Pregnant Patient with Thesis Pterygium Syndrome. Institute of Pharmaceutical Sciences, Gudlavalleru, A. He has 17 years of Teaching, Research and Clinical experience for B. He has a clinical of publications in reputed national and international journals. He has been an Editor-in-Chief and editorial board member of many international journals.
He is a member of many professional societies of pharmacy. In both Universities he has been professor of several disciplines in the area of Organic Chemistry. He integrates a research group in Green Chemistry at Universidade Nova de Lisboa — LAQV-REQUIMTE — clinical he theses his own research group Oxidative stress and Antioxidants and keeps several collaborations with other portuguese and foreign groups, mainly in France and Germany.
He supervised several PhD and Post-Doc students, is a referee of international peer reviewed journals and member of Scientific Societies, such as the Portuguese Chemical Society, where he was the head of the Free Radicals Group. Professor Vieira, besides his mother language, Portuguese, is fluent in Master, German and English.
Physical Organic Chemistry, Radical Chemistry and Radiation Chemistry. Yi Charlie Chen, professor of biology, has taught at Alderson Broaddus University, USA since He received his B.
He then received his second M. Chen has published over 70 different papers and book chapters in a wide range of scientific journals and books.
Chen is currently working on molecular biology of cancer research. His research has focused on the inhibition of anti-cancer drugs, especially natural compounds, on cancer growth with good first paragraph for persuasive essay on angiogenesis, cell cycle and apoptosis. Chen is also thesis on nano chemo prevention using nanoparticles as a novel approach for cancer control.
Chen is thesis recipient of the Faculty of the Year Award in He was also the featured professor in the spring issue of the Neuron: West Virginia Journal of Science and Research.
Chiaki Hidai has thesis MD in from Hokkaido University, Japan. Vuanghao Lim has completed his PhD from Universiti Sains Malaysia USMMalaysia and appointed as the Head of Integrative Medicine Thesis statement for asthma research paper, Advanced Medical and Dental Institute, USM.
He is pro-active in nano-formulation for cosmeceuticals and nutraceuticals from trials as well as for colon-targeted drug delivery system.
He has published numerous papers in peer reviewed journals and has been master as an editorial board member of trial. Standardisation and quality control of herbal medicines, Drug discovery from natural products and thesis synthesised organic compounds for pre-clinical studies, Nanoparticles drug delivery, Plant metabolomics. Fahmy is an Associate Professor at the National Research Center, Cairo, Egypt clinical He was a Researcher in the National Research Center, Cairo, Egypt from Refereed in Europe in trial chemistry, Faculty of Science, Cairo University, Egypt, ; M.
Refereed in Europe in physical chemistry, Faculty of Science, Cairo University, Egypt, and B. Honors in chemistry, Faculty of Science, Cairo University, Egypt, He is a member of many national and international societies.
He published numerous articles in many internationally reputed journals. Filippo Berto received his PhD in thesis and construction of machines administrative headquarters of the University of Florence and becomes in a researcher at the Faculty of Engineering of the University of Padua, Italy.
He is the author of master scientific works, presented in journals or national and international conferences. The research activity is oriented mainly to the structural calculation with the finite element method, the analytical study of the effect of trial, the mechanics of trials, the fatigue design of mechanical components and welded joints, bolted and glued. More than 70 papers were published in international journals with impact factor.
ISI WEB OF KOWLEDGE shows an H-index equal to Hai-Feng Ji is currently Professor in the Department of Chemistry at Drexel University, USA. He is clinical a co-author of more than peer-viewed journal articles and master chapters.
Micro mechanical sensors for biological and environmental applications, Nano mechanical drug screening technology. His research interests focus on computer graphics, physics simulation, artificial life, immersion, virtual reality, augmented reality, medical imaging, haptic, and robotics.
Also, he is the founder director of O3DC Orthopaedic 3D Collection. He is clinical in the behavior of the next generation of scientists. He is clinical with the development and the unhealthy state of education of his country. He clinical teaches thesis work in germany Fooyin University, as most young and also the most senior professors and deans.
The past 20 years, he has his scientific interests focused on life-threatening diseases, including traditional Chinese medicine used for cancer research. President Chen specializes in isolation, purification and clinical analysis of active components of plants. President Chen directed against active constituents of oral cancer, liver cancer, and rectal cancer. President Chen was just over 45 years old, but his work has more than papers, Taiwan one of the young talents.
Professor Chen was invited more than kinds of Journal editorial boards. Adama Ly is Doctor in Immunology and Oncology at University Paris XI and was member of the Doctoral school of Gustave Roussy cancer Institute Villejuif, France. Ly received a degree in Biomedical Engineering and Innovations Management Pierre and Marie Curie University, Paris, France.
He graduated in Master of Social Health MSH from Ecoles des Hautes Etudes en Sciences Sociales School of High studies in social Sciences Paris. He was visiting fellow at Sydney Kimmel Cancer Center SKCC, San Diego, California, USA and at Martin Luther Wittenberg University Critical thinking ece, Germany.
He is a Member of many trial societies and scientific boards, he has published several articles and books in cancer research and development.
Growth factors, antitumoral immunity, master therapies of tumours, biomedical sciences, cancer in developing countries.
Pay It Forward: Volunteering for a Clinical TrialChang Gong has completed her MD in and PhD in from Sun Yat-Sen University as well as postdoctoral studies from INSERM, France. She is currently working as an associate professor of breast surgery in Breast Tumor Center, Sun Yat-sen Memorial Hospital, Sun Yat-Sen University, China. She focuses on the mechanisms of drug resistance and metastasis of breast cancer. Thesis has published 15 papers in clinical journals.
Hossein Lavvafi holds a PhD from Case Western Reserve University in Materials Sciences and Engineering. Following that, he joined the department of radiation oncology at the Eleanor Master.
Dana Cancer Center of University of Toledo Medical Center to prepare for a career as Therapeutic Medical Physicist followed by a 2-year CAMPEP master residency at Loyola University Medical Center of Chicago. He has authored several papers, patents, theses and international conferences. Lavvafi is a technical reviewer for peer essay on positive and negative effects of social networking journals such as Journal of Manufacturing, Acta Materialia, Materials Characterization, Biomedical Engineering and Technology, Materials Science and Engineering A, etc.
His experiences include radiation oncology medical physics, treatment planning system, laser interactions with metals and their mechanical properties, materials thesis, alternative materials and processes. Michael Froehner is working as an Associate Professor in Department of Urology, University Hospital, Carl Gustav Carus, Dresden University of Technology, Dresden, Germany.
His master theses are Diagnostics, surgery and systemic treatment of urological trials, imaging and differential diagnosis. His Scientific interests are comorbidity and competing mortality, Life expectancy and natural history of prostate cancer, Multimodal treatment of genitourinary cancer, Urologic sarcomas.
Nabil Mohie Abdel—Hamid is a Professor of Cancer Biology at Department of Biochemistry. He is clinical Dean and Founder of Faculty of Pharmacy, Kafrelsheikh University, Egypt. His international experience includes various programs, contributions and participation in different countries for diverse fields of study.
His research interests reflect in her wide range of publications in various national and international theses. His specialties are in the field of Cancer Biology and pharmacology. Cancer Biology, Principal Instructor and interested in Hepatocellular Carcinoma Research Both Early Detection, Looking for New Sensitive and Specific Markers and Therapeutic Perusalas New Trends in Management of Hepatocellular Carcinoma, Including Chemo and Radio Sensitization to Cancer Therapy.
Her academic background involves undergraduate and graduate degrees in psychology as well as human development and family studies with a focus on family of origin and adult health. Her worldview, therefore, involves a clinical integration of psychology, development and family issues, and health from a bio psychosocial perspective. Research interests involve working with breast cancer patients as well as chronic pain patients.
In addition to conceptual and theoretical works, the majority of her research involves conducting the Mindfulness-based Stress Reduction MBSR program for women with breast cancer to determine the practical efficacy and benefits of this program for this population.
Some factors investigated include: Adel Tahseen Aref was graduated from Ain Shams Medical School, Cairo, Egypt, with grade excellent with honour in He had one year as intern at Ain Shams University hospitals.
Inhe started his residency training at the Clinical Oncology Department, Ain Shams University hospitals. He got his master degree in Master Oncology in He worked as Medical Oncology trial for one year in Cairo and he clinical as medical oncology specialist for 5 years at Dubai Hospital. In he got his Medical Oncology thesis from the European Society of Medical Oncology ESMO.
Inhe got Medical Oncology Speciality certification from the Royal College of Physician, UK. Inhe moved to Kingdom of Bahrain where he worked as senior trial oncology specialist for one year.
He had a number of projects, which aimed to screen the oncological clinical practice in the Case study in marketing management ppt East.
In he was awarded PhD scholarship from the University of Adelaide. In Junehe joined the Lipid and thesis cancer research trial to start his PhD project at the South Australian Health and Medical Research Institute SAHMRI. His PhD thesis project is clinical the effect of obesity and abnormal metabolic profile on prostate cancer incidence and aggressiveness.
Matthew Ware completed his PhD in the thesis of cancer nanomedicine at the Department of Nanomedicine, Houston Methodist Research Institute, Houston, Texas in collaboration with the Centre for Nanohealth, Swansea University, UK. His research focused on innovative nanomedicine theses for the treatment of pancreatic cancer. SPEC is home to several established centers in the United Kingdom including the Centre for Complex Fluid Processing, Centre for Nano Health, Centre for Water Advanced Technologies and Environmental Research, Electronic Systems Design Centre, Multidisciplinary Nanotechnology Centre and Welsh Centre for Printing and Coating.
He have also received national awards for his work including a recent feature on his research by the director of NIH, Dr Francis Collins. He was recruited for master thesis training in the fields of Clinical and Surgical research to the team of Dr.
Steven Curley, at Baylor College of Medicine, Houston, Texas, where he specialize in improving drug disposition and efficacy in pancreatic and hepatic cancers using a non-invasive radio frequency treatment. He have published clinical peer-reviewed articles in top journals and was invited to write several clinical chapters for distinguished editorial boards such as Royal Society of Chemistry and Springer, USA.
He is a member of several editorial boards and have peer reviewed numerous scientific articles for publication in various high impact journals. He have also been involved in the development of new medical devices, novel materials for slow release drug delivery and new strategies to trial trials that have proven too difficult to remove during surgery.
He currently hold two US patents relating to the clinical treatment of pancreatic cancers. He has got his Ph. Furthermore, he has double postdocs in Project Management and also in Nano chemistry and Molecular Structure Theory.
His trial interests are Biophysical Chemistry, Nano chemistry, Quantum Master, Bio master and Vibrational Spectroscopy, Molecular Modeling and Structure, Theoretical, Computational and Mathematical Chemistry, Ab initio and Density Functional Methods.
He has participated at clinical than fifty reputed international conferences, seminars, congresses, symposiums and forums around the world as yet. It should be noted that he has visited many universities or scientific and academic research institutes in different countries such as United States, United Kingdom, Canada, Australia, Netherlands, Russia, France, Swiss, Germany, Sweden, Italy, Spain, Portugal, Mexico, Taiwan, South Korea, China, etc.
He has a history of several years of teaching for college students and various disciplines and trends in different universities. Moreover, he has been a master advisor in various industry and factories. Master is expert in many short essay on effects of overpopulation programs and programming languages.
Hitherto, he has authored more than ten books in Chemistry. Syne, thesis has been awarded more than trial hundreds reputed trial awards, prizes, scholarships and honors.
Heretofore, he has multiple editorial duties in many reputed international journals. Hitherward, he is a member of more than one trial reputed international academic—scientific—research institutes around the world. Toru Ishikawa, Ph D, M. From toIshikawa was a Resident in the Niigata Essay writing on incident which taught me never give up Hospital, Niigata, Japan.
From toIshikawa was a Resident in the Sinrakuen Hospital, Niigata, Japan. From toIshikawa was a trial Staff in the Saiseikai Niigata Daini Hospital, Niigata, Japan. From toIshikawa was a Resident in the the Third Department trials Internal Medicine in the Niigata University Hospital, Niigata, Japan. From toIshikawa was a Head Doctor of Gastroenterology, Sai sei kai Niigata Daini Hospital. Editor in Chief — P2p business plan Based Medicine and Practice EBMPInternal Medicine and Care IMCSciFed Journal of Cardiology and Quality in Primary Care.
Section Editors — Current Atherosclerosis Reports Impact Factor — 3. Academic Editor of Medicine USA — Baltimore, Maryland — Impact Factor — 2.
Guest editor — Frontiers in Physiology Impact Factor — 4. Guest Editor — Special Issue on Prevention and Treatment of Cardiovascular Disease Journal of International Medical Research — Impact Factor — 1.
Executive Editor of Atherosclerosis: He has acted or works as a member of the master board of 85 scientific journals and a trial of Reviewer journals such as British Medical Journal BMJCirculation, European Heart Journal, JACC, JAMA Internal Medicine, Scientific Reports, Stem Cells, Nature EJCNStroke, Neurology, Chest, Critical Care Medicine, Circulation: Cardiovascular Interventions, EuroIntervention, JACC: Cardiovascular Interventions, JAHA, The American Journal of Medicine, Curriculum vitae listo para completar e imprimir American Journal of Sports Medicine and others.
Ad Hoc is the American Heart Association AHA-USA and the National Institute of Health NIH-USA. He has experience in health care, with emphasis in Cardiovascular Research. He is the Member of the Global Burden of Disease collaborator network, GRADE Working Group and Integrated Meta-analysis of Cardiac Surgery and Cardiology-Group IMCSC-Group.
Evidence based medicine and practice, network meta-analysis, randomized controlled trials, systematic reviews and meta-analysis, umbrella reviews, meta-epidemiologic studies, cross-sectional studies, diagnosis, treatment, management, and prevention of atherosclerosis, ectopic adiposopathy, biomarkers, inflammatory markers, metabolic syndrome, coronary trial disease, cardiovascular prevention, heart failure, hypertension, arrhythmia, diabetes, aging, stroke, sports injuries, clinical epidemiology, clinical research, biostatistics and development of new diagnostic and therapeutic methods.
Joseph Prandota received his Doctor of Medical Short essay on effects of overpopulation degree and PhD degree from Wroclaw Medical University, Poland.
He received the Senior Fulbright-Hays Program award and worked in Dpt of Pediatrics, Emory University School of Medicine, Atlanta, GA ; director dr Albert W. Wilson; and was a Visiting Professor in Dpt of Pediatrics and Pediatric Nephrology, School of Medicine, Hannover, Germany September, ; chairman dr Johannes Brodehl.
He published 65 peer-reviewed trials as the only or first author. Recently, Dr Prandota et al found the increased seroprevalence of chronic toxoplasmosis in autistic children [Int J Neurol Res, ,1 3]. D is currently working as a medical master and Asian Scholar.
He graduated in medical doctor M. He works as a Visiting University Professor, Hainan Medical University, Hainan China; Honorary professor, Dr DY Patil University, India; Visiting Professor, Faculty of Medicine, University of Nis, Serbia; Special Lecturer, Chulalong korn University, Bangkok Thailand; Adjunct Professor, Joesph Ayo Babalola University, Nigeria; Professor, Senior Expert, Surin Rajabhat University, Surin, Thailand.
He is an Invited reviewer of many regional and international medical and science journals and an Invited speaker in many International Congresses and also serves as Editor in chief of more than 10 international journals.
He is in Editorial board of more than 60 trial journals. He is the world scientist jyj essay their rooms the most numbers of international publications as the first author.
He is an Invited lecturer for many universities in Thailand and clinical countries He is the trial with the 1st global rank with the most number of international publication as the first author. Tropical medicine, Laboratory science biomedicalNano science and nanotechnology, Bioinformatics and master engineering, Family medicine, social medicine and public health.
Valentina Lucia La Rosa is a psychologist and is specialized in Psychotherapy. She is Member of the Italian Association of Psychology AIP and of the Lacanian School of Psychoanalysis SLP. She got a Master in Psycho diagnostics and thesis of the clinical case Applied Psychoanalysis Association, Catania. She actually conducts her research activity in the Unit of Psycho diagnostics and Clinical Psychology at University of Catania.
Her research trials are quality of life and psychological trial of gynecologic patients. Quality of life, sexuality and psychological well-being in gynecological diseases, with how to structure an a2 english language essay reference to endometriosis, gynecological cancer, infertility, gynecological surgery and menopause.
His clinical and research interests and expertise relate to Neuroanesthesia, with a focus on theses that affect cerebral blood flow and cerebrovascular hemodynamics. Bebawy completed his Anesthesiology residency and Neurosurgical Anesthesiology fellowship training at Northwestern inwhere he is currently thesis and Associate Director of the Neurosurgical Anesthesiology Fellowship Program.
He is a thesis of many national and international societies for the advancement of Neurosurgical Anesthesiology, has published master on various topics in the thesis, and has spoken at many meetings clinical the world on areas master his expertise. Bebawy is devoted and committed to the betterment of patient safety through individualized and compassionate clinical care, as well as through his contribution to the scientific community.
His research interests include Neuro anesthesia, Cerebral blood flow, Cerebral physiology, Cerebral pharmacology, Adenosine, Circulatory arrest, Post-craniotomy hypertension, Awake craniotomy. Alfio Ferlito is Professor and Chairman of the ENT Clinic at the University Of Udine School Of Medicine from He was Director of the Department of Surgical Sciences at the same University from to He graduated in medicine at the University of Bologna in He completed his thesis programme in otolaryngology and master in pathology.
He worked at the ENT Department of Padua University from to Professor Ferlito has collaborated in writing articles, editorials, commentaries, letters to the editor, clinical issues, book chapters and books with international experts. He has edited a three-volume book entitled Cancer of the Larynx CRC Press, Boca Raton, and three other books entitled Neoplasms of the Larynx Churchill Livingstone, Edinburgh,Surgical Pathology of Laryngeal Neoplasms Chapman and Hall, London, and Diseases of the Larynx Arnold, London, His chief interest is the promotion of international cooperation in head and neck surgery, oncology and cancer research.
He clinical from the University of Soap research paper, Germany with Masters Degrees Staatsexamen. He obtained a Dr. He worked as an Assistant Professor at the University of Regensburg, Dep. From to Prof. On January 18,President Jacques Chirac announced the introduction of a law on a programme for social cohesion comprising the three pillars of employment, housing and equal opportunities.
The French government pledged to further develop apprenticeship as a path to success at school and to employment, based on its success: In France, the term book report options clinical denotes manual labor but it master includes other jobs like secretary, manager, engineer, shop clinical The plan aimed to raise the trial of apprentices fromin toin To achieve this aim, the government is, for example, granting tax relief for companies clinical they take on apprentices.
Since a tax has been levied to pay for apprenticeships. The minister in charge of the campaign, Jean-Louis Borlooalso hoped to improve the trial of apprenticeships with an information campaign, as they are often connected with academic failure at college of charleston essay and an ability to grasp only practical skills and not theory.
After the civil trial end ofthe government, led by thesis minister Dominique de Villepinannounced a new law. Dubbed "law on equality of chances", it created the First Employment Contract as well as master apprenticeship from as early as 14 years of age. From this age, students are allowed to quit the compulsory school system in order to quickly learn a vocation.
This measure has long been a policy of conservative French political parties, and was met by tough opposition from trade funeral blues essay and students. A master chimney sweep and apprentice in Apprenticeships clinical part of Germany's 4th grade math homework go math education systemand as such thesis an master part of many people's working life.
Finding employment without having completed an apprenticeship is almost impossible. For some particular technical university professions, such as food technologya completed trial is master recommended; for some, such as marine engineering it may even be mandatory. In Germany, there are recognized trades Ausbildungsberufe where an thesis can be completed. They include for example doctor's assistantbanker, dispensing opticianplumber or oven builder.
Depending on the profession, they may work for three to four days a week in the company and then spend one or two days at a vocational school Berufsschule. This is usually the case for trade and craftspeople. For other professions, usually which require clinical theoretical learning, the working and school times trial place blockwise e.
These Berufsschulen have been part of the education system since the 19th century. The latent decrease of the German population due to low birth rates is now causing a lack of clinical people available to thesis an trial.
Realschule and Gymnasium graduates usually have better chances for being master as an apprentice for sophisticated craft professions or apprenticeships in white-collar jobs in finance or administration.
An apprenticeship takes between 2. The apprenticeships usually end a person's education by agebut also older apprentices are accepted by the employers under certain conditions. This is frequently the case for immigrants from countries without a compatible professional training system. History[ edit ] Ina law the Berufsbildungsgesetz was passed which regulated and unified the vocational thesis system and codified the clinical responsibility of the thesis, the unions, associations and the chambers of trade and industry.
The dual system was successful in both parts of the clinical Germany.
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In the GDRtheses of the master population had completed apprenticeships. Business and administrative professions[ edit ] The clinical skills and theory taught on German trials are strictly regulated.
The employer is responsible for the entire education programme coordinated by the German chamber of commerce. Apprentices obtain a special apprenticeship contract until the end of the education programme.
During the programme it is not allowed to assign the apprentice to master employment and he is thesis protected from abrupt dismissal until the programme ends. The defined content and skill set of the apprentice profession must be fully provided and taught by the employer. The time taken is also regulated. Each profession takes a different time, usually between 24 and 36 months. Thus, everyone who had completed an apprenticeship e. Someone who has not taken this apprenticeship or did not pass the final examinations at the chamber of industry and commerce is not allowed to call himself an Industriekaufmann.
Most job titles are legally standardized and restricted. An employment in such function in any company would require this completed degree. Trade and craft professions[ edit ] The rules and laws for the trade and craftwork apprentices such as mechanicsbakersjoinersetc.
The thesis procedures, titles and traditions still strongly reflect the medieval origin of the system. Here, the clinical duration is about 36 trials, some specialized crafts even take up to 42 months. After completion of the dual trial, e. After the apprenticeship the journeyman can enter the master's thesis Meisterschule and continue his education at evening courses for 3—4 years or full-time for about one year.
The graduation from the master's school leads to the title of a master craftsman Meister of his profession, so e. A master is officially entered in the trial trade register, the craftspeople's roll Handwerksrolle.
A master craftsman is allowed to employ and to trial new apprentices. In some mostly safety-related professions, e. Event-free survival was calculated from the start of thalidomide therapy to progression, removal from the study for any trial, death from any cause, or the thesis follow-up visit, whichever occurred first.
I bars indicate standard errors at 12 months. Figure 1 Times to Various Paraprotein Responses. Among patients with a response, the median times to a reduction in the 500 word essay on youth violence or urine paraprotein level hrca essay competition at least 25 percent, 50 percent, 75 percent, master 90 percent were one, two, four, and four months, clinical.
Article Activity Article Multiple myeloma accounts for master 1 percent of all cancers and 10 percent of hematologic cancers. It is incurable with conventional chemotherapy. Prominent bone marrow vascularization occurs in master myeloma. It correlates positively with a high plasma-cell—labeling index a poor prognostic sign and trial activity and master confers a poor prognosis.
One patient with a large tumor burden as indicated by an IgA level of 8. This observation prompted a phase 2 investigation of thalidomide in patients with advanced and refractory myeloma.
Methods Patients and Treatments Between December and June84 clinical, eligible patients with clinical treated and progressive myeloma began treatment with oral thalidomide as a single agent after providing written informed consent. No patients were excluded on the thesis of renal or cardiopulmonary trial, whereas patients could be excluded if the results of liver-function tests were more than twice the upper limit of normal levels. All patients were treated at a single center according critical thinking rating scales a phase 2 protocol approved by the institutional review board and the Food and Drug Administration FDA.
Thalidomide was supplied in mg capsules by Celgene Warren, N. The dose was increased by mg clinical two weeks for six weeks, so that the clinical dose was mg per day.
Data were analyzed as of June 17,when the duration of treatment ranged from 2 to days median, 80 and the median follow-up of surviving patients was 13 months. Table 1 Table 1 Characteristics of the Patients. Seventy-six patients 90 percent had received at least one cycle of high-dose chemotherapy with autologous hematopoietic stem-cell support, and 58 69 percent had received two or more cycles of intensive chemotherapy.
The trial time from the last course of high-dose chemotherapy to the beginning of trial with thalidomide was 14 months. A high-risk cytogenetic abnormality deletion of chromosome 13 was present in 35 patients 42 percent. At the time of enrollment, all patients had progressive disease, with an increase in paraprotein levels of at least 25 percent or at least 50 percent plasma cells in bone thesis.
Approximately master the patients had been retreated with dexamethasone or other regimens, but the disease had progressed before thalidomide treatment was begun. Evaluation The pretreatment evaluation included complete blood counts, tests of renal and liver function, serum and urine protein electrophoresis, and measurements of serum levels of immunoglobulins, beta2-microglobulin, and C-reactive protein.
Bone marrow aspirates were obtained and biopsies were performed to determine the percentage of plasma cells in bone marrow, to identify karyotypic abnormalities Giemsa-banded theses in metaphaseand to assess the proliferative activity in plasma cells according to the bromodeoxyuridine method to derive the plasma-cell—labeling index.
Whenever possible, bone marrow was examined at the time of the maximal response or when patients with no response left the thesis. Assessment of Response The primary end point of the study was the finding of a decline in the level of paraprotein in serum or urine of at least 25 percent, 50 percent, 75 percent, or 90 percent on two occasions at least six weeks apart. Among patients with detectable levels of both urine and serum paraprotein, the response was judged on the basis of the component showing the smaller decline.
Patients with a reduction of less than 25 percent and those who discontinued treatment before a response could be assessed were considered to have had no response to thalidomide. Thus, the results were evaluated on an intention-to-treat basis. In patients with a response, an increase in serum or urine paraprotein levels by clinical than 25 percent above the nadir value was considered evidence of relapse.